Open study of the safety and efficacy of a single oral dose of cefixime for the treatment of gonorrhea in pregnancy.

Abstract

OBJECTIVE:

The intent of this study was to determine the efficacy and tolerance of single dose oral cefixime use in the treatment of pregnant women with endocervical gonococcal carriage.

METHODS:

A retrospective review of clinic records over a 3 year period identified patients treated with a single 400 mg dose of cefixime for gonorrhea during pregnancy. Side effects and subsequent gonococcal carriage were noted.

RESULTS:

Pregnant women (n = 102) treated with cefixime were reviewed. A cure rate of 95.2% was found. Side effects were reported in three patients: two had nausea and vomiting and one had diarrhea.

CONCLUSIONS:

A single 400 mg oral dose of cefixime was effective for the treatment of gonorrhea and was well tolerated by the pregnant women.

• Authors: J M Miller
• Journal: Infectious diseases in obstetrics and gynecology (Infect Dis Obstet Gynecol) Vol. 5 Issue 3 Pg. 259-61 ( 1997) ISSN: 1064-7449 [Print] Egypt
• PMID: 18476147 (Publication Type: Journal Article)