[Anidulafungin: experimental therapy of fungal infections in animal models].

Abstract

We have reviewed the existing data on the efficacy of anidulafungin, which is the most recent echinocandin in the experimental treatment of fungal infections. The scarce published data practically only refers to disseminated and pulmonary aspergillosis and to disseminated candidiasis. Anidulafungin shows fungistatic activity against Aspergillus fumigatus, and fungicidal activity against Candida albicans and Candida glabrata.

• Authors: Francisco Javier Pastor, Josep Guarro
• Journal: Revista iberoamericana de micologia (Rev Iberoam Micol) Vol. 25 Issue 2 Pg. 119-23 (Jun 2008) ISSN: 1130-1406 [Print] Spain
• Vernacular Title: Anidulafungina en el tratamiento de la infección fúngica en modelos animales.
• PMID: 18473506 (Publication Type: Journal Article, Review)

Chemical References

• Antifungal Agents
• Echinocandins
• Anidulafungin

Topics

• Anidulafungin
• Animals
• Antifungal Agents (therapeutic use)
• Aspergillosis (drug therapy)
• Candidiasis (drug therapy)
• Disease Models, Animal
• Echinocandins (therapeutic use)
• Lung Diseases, Fungal (drug therapy)