Severe hyperglycemic hyperosmolar nonketotic coma in a nondiabetic patient receiving aripiprazole.

Abstract

Aripiprazole is commonly used as an atypical antipsychotic. It has been associated with abnormalities in glucose metabolism. Severe diabetic complications associated with its use occur rarely. We present a case of a patient without a history of diabetes mellitus who presented to the emergency department in severe hyperosmolar nonketotic coma while using aripiprazole.

• Authors: Lisa Marie Campanella, Richard Lartey, Richard Shih
• Journal: Annals of emergency medicine (Ann Emerg Med) Vol. 53 Issue 2 Pg. 264-6 (Feb 2009) ISSN: 1097-6760 [Electronic] United States
• PMID: 18468728 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antipsychotic Agents
• Piperazines
• Quinolones
• Aripiprazole

Topics

• Antipsychotic Agents (adverse effects)
• Aripiprazole
• Humans
• Hyperglycemic Hyperosmolar Nonketotic Coma (blood, chemically induced)
• Male
• Middle Aged
• Piperazines (adverse effects)
• Quinolones (adverse effects)
• Schizophrenia (drug therapy)