Evaluation of the effectiveness of peracetic acid in the sterilization of dental equipment.

Abstract

PURPOSE:

To evaluate the effectiveness of peracetic acid in the microbiological sterilisation of dental materials.

METHODS:

Peracetic acid solution was evaluated at concentrations of 800, 1500 and 2500 ppm. At these concentrations, it was determined whether peracetic acid caused corrosion to dental instruments and induced cellular mutagenicity and cytotoxicity. In addition, the minimum inhibitory concentration (MIC), the minimum bactericidal concentration (MBC), agar diffusion and diffusion by well method, were also verified.

RESULTS:

The corrosion rate, calculated from potentiodynamic assays was 10(-6) cm/year, indicating that the product does not damage equipment. The sterilisation capacity of peracetic acid at 2500 ppm was the best. The comet assay indicated genotoxic activity at 2500 ppm.

CONCLUSIONS:

This study demonstrated the effectiveness of peracetic acid for sterilizing dental equipment, providing another alternative for the prevention of infections in clinics.

• Authors: R Ceretta, M M S Paula, Ev Angioletto, M M Méier, F G Mitellstädt, C T Pich, S A Junior, E Angioletto
• Journal: Indian journal of medical microbiology (Indian J Med Microbiol) 2008 Apr-Jun Vol. 26 Issue 2 Pg. 117-22 ISSN: 0255-0857 [Print] United States
• PMID: 18445945 (Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Disinfectants
• Tetrazolium Salts
• Thiazoles
• DNA
• thiazolyl blue
• Peracetic Acid

Topics

• Bacteria (drug effects)
• Blood Cells (drug effects)
• Cell Survival
• Comet Assay
• DNA (drug effects)
• Dental Equipment (microbiology)
• Disinfectants (pharmacology, toxicity)
• Disinfection (methods)
• Humans
• Microbial Sensitivity Tests
• Peracetic Acid (pharmacology, toxicity)
• Phagocytes (drug effects)
• Tetrazolium Salts (metabolism)
• Thiazoles (metabolism)