Abstract | PURPOSE: MATERIALS AND METHODS: Adult male Sprague-Dawley rats (National Science Council, Taipei, Taiwan, Republic of China) were allocated to undergo testicular torsion-detorsion immediately followed by injection of normal saline, hemin or hemin plus tin protoporphyrin, a heme oxygenase-1 inhibitor. Another set of rats that underwent sham operation were used as controls. Testes were harvested 0 and 30 minutes after detorsion and enzyme expression was analyzed. RESULTS: CONCLUSIONS:
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Authors | Stone Yang, Hung-Jen Shih, Yung-Chiong Chow, Pei-Shan Tsai, Chun-Jen Huang |
Journal | The Journal of urology
(J Urol)
Vol. 179
Issue 6
Pg. 2456-63
(Jun 2008)
ISSN: 1527-3792 [Electronic] United States |
PMID | 18433787
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- NF-E2-Related Factor 2
- NF-kappa B
- Hemin
- Heme Oxygenase (Decyclizing)
- Hmox1 protein, rat
- Extracellular Signal-Regulated MAP Kinases
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Topics |
- Animals
- Disease Models, Animal
- Extracellular Signal-Regulated MAP Kinases
(physiology)
- Heme Oxygenase (Decyclizing)
(biosynthesis)
- Hemin
(physiology)
- Male
- NF-E2-Related Factor 2
(physiology)
- NF-kappa B
(physiology)
- Rats
- Rats, Sprague-Dawley
- Spermatic Cord Torsion
(enzymology, metabolism)
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