[Somatostatin analogues in the treatment of bleeding GI-angiodysplasias].

Abstract

Angiodysplasias account for 2-8% of GI-bleeding episodes. We describe a 75-year-old patient with a history of anaemia for 1 year before being diagnosed with multiple angiodysplasias in the GI-tract. The patient needed weekly blood transfusions until he started treatment with octreotide. After 4 months of treatment the need for transfusions had decreased dramatically and faeces was negative for blood. Treatment was switched to long-acting octreotide (Sandostatin Lar). The case illustrates the usefulness of somatostatin analogues in the treatment of bleeding GI-angiodysplasias.

• Authors: Lene Boesby, Niels Juel Christensen, Lars Ostergaard Kristensen
• Journal: Ugeskrift for laeger (Ugeskr Laeger) Vol. 170 Issue 11 Pg. 958 (Mar 10 2008) ISSN: 1603-6824 [Electronic] Denmark
• Vernacular Title: Behandling af gastrointestinal blødning fra angiodysplasier med somatostatinanalogen octreotid.
• PMID: 18397628 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Gastrointestinal Agents
• Octreotide

Topics

• Aged
• Anemia (etiology)
• Angiodysplasia (complications)
• Blood Transfusion
• Gastrointestinal Agents (therapeutic use)
• Gastrointestinal Hemorrhage (complications, etiology)
• Humans
• Male
• Octreotide (therapeutic use)