Anti-anginal efficacy of intravenous amlodipine assessed by means of atrial pacing.

Abstract	The anti-anginal efficacy of amlodipine was investigated in patients with angina pectoris by means of atrial pacing during cardiac catheterization. Intravenous administration of amlodipine significantly increased the time to pacing-induced angina and reduced the area of ST-segment change for an equivalent pacing rate, suggesting an improvement in this functional marker of ischaemia. In addition, a significant reduction in the double product suggests that amlodipine reduced myocardial oxygen consumption.
Authors	K J Hogg, R S Hornung, W S Hillis, S Gupta, P Grant, S P Singh
Journal	Postgraduate medical journal (Postgrad Med J) Vol. 67 Suppl 5 Pg. S57-8 ( 1991) ISSN: 0032-5473 [Print] England
PMID	1839443 (Publication Type: Journal Article)
Chemical References	Calcium Channel Blockers Amlodipine Nifedipine
Topics	Amlodipine Angina Pectoris (drug therapy) Calcium Channel Blockers (administration & dosage) Cardiac Pacing, Artificial Electrocardiography Humans Injections, Intravenous Nifedipine (administration & dosage, analogs & derivatives)

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