Abstract | INTRODUCTION: CASE PRESENTATION: We present the case of a 74-year-old man with Castleman's disease. The disease was detected with a contrast-enhanced computed tomography (CT) scan and a fluorodeoxyglucose (FDG)-positron emission tomography (PET)/CT study; diagnosis was made with histopathology. After treatment with surgical excision followed by chemotherapy, the disease response was evaluated using both diagnostic techniques. However, only the PET study was able to identify the spread of the disease to the abdominal lymph nodes, which were both enlarged and normal size, and, after treatment, to evaluate the disease response. CONCLUSION: Based on the results of previous case reports and on those of the present study, it seems that Castleman's disease has a high glucose metabolic activity. Therefore, the use of PET can be considered appropriate in order to stage or restage the disease and to evaluate the response of the disease to treatment.
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Authors | Ettore Pelosi, Andrea Skanjeti, Angelina Cistaro, Vincenzo Arena |
Journal | Journal of medical case reports
(J Med Case Rep)
Vol. 2
Pg. 99
(Apr 03 2008)
ISSN: 1752-1947 [Print] England |
PMID | 18387191
(Publication Type: Journal Article)
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