[Retrospective study on clinical application of biovalves in 52 cases].

Abstract

OBJECTIVE:

To summarize the clinical application of bioprosthetic valve replacement.

METHODS:

Fifty two patients, aged 13-73(52.4+/-14.0) years, underwent cardiac valve replacement with biovalves from June 2002 to June 2006 in our hospital. Fifty three tissue valve replacements combined with 8 mechanical valve replacements were performed. Other procedures were also carried out if appropriate, including bidirectional Glenn shunt in 1 patient with double outlet of right ventricle and pulmonary artery stenosis; interruption of accessory pathway in 1 patient with Wolff-Parkinson-White syndrome; coronary artery bypass graft in 5 with severe coronary artery disease; and atrial or ventricular repair in 4 with congenital septum defects.

RESULTS:

One patient died in hospital due to multiple organ failure. The hospital mortality rate was 1.9%. The mean follow-up was 25 months. Two patients lost follow-up and the follow-up rate was 96%. Forty one patients returned to NYHA class I, 9 to class II, and 1 to class III. Echocardiography showed the implanted bioprosthesis functioned well without stenosis or regurgitation. There was no structural deterioration with freedom from thromboembolism and anticoagulant hemorrhage in all patients.

CONCLUSION:

The efficacy of biovalves in heart valve replacement is satisfactory.

• Authors: Feng Li, Jian-guo Hu, Bang-liang Yin, Jin-fu Yang, Tao Tang, Hua Gao
• Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences (Zhong Nan Da Xue Xue Bao Yi Xue Ban) Vol. 33 Issue 3 Pg. 257-61 (Mar 2008) ISSN: 1672-7347 [Print] China
• PMID: 18382062 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adolescent
• Adult
• Aged
• Bioprosthesis
• Female
• Follow-Up Studies
• Heart Valve Prosthesis
• Heart Valve Prosthesis Implantation (methods)
• Humans
• Male
• Middle Aged
• Mitral Valve (surgery)
• Retrospective Studies
• Tricuspid Valve (surgery)