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A loss of function polymorphism (G191R) of anionic trypsinogen (PRSS2) confers protection against chronic pancreatitis.

AuthorsSundaresan Santhosh, Heiko Witt, René H M te Morsche, Zsofia Nemoda, Tamás Molnár, Akos Pap, Jan B M J Jansen, Joost P H Drenth
JournalPancreas (Pancreas) Vol. 36 Issue 3 Pg. 317-20 (Apr 2008) ISSN: 1536-4828 [Electronic] United States
PMID18362849 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • DNA Primers
  • PRSS2 protein, human
  • Trypsinogen
  • Trypsin
Topics
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Alleles
  • Amino Acid Substitution
  • Base Sequence
  • Case-Control Studies
  • Child
  • DNA Primers (genetics)
  • Female
  • Gene Frequency
  • Heterozygote
  • Humans
  • Hungary
  • Male
  • Middle Aged
  • Pancreatitis, Chronic (genetics, prevention & control)
  • Polymorphism, Single Nucleotide
  • Trypsin (genetics)
  • Trypsinogen (genetics)

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