Abstract |
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Authors | L S Steelman, P M Navolanic, M L Sokolosky, J R Taylor, B D Lehmann, W H Chappell, S L Abrams, E W T Wong, K M Stadelman, D M Terrian, N R Leslie, A M Martelli, F Stivala, M Libra, R A Franklin, J A McCubrey |
Journal | Oncogene
(Oncogene)
Vol. 27
Issue 29
Pg. 4086-95
(Jul 03 2008)
ISSN: 1476-5594 [Electronic] England |
PMID | 18332865
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antibiotics, Antineoplastic
- Doxorubicin
- Protein Kinases
- MTOR protein, human
- Proto-Oncogene Proteins c-akt
- Ribosomal Protein S6 Kinases, 70-kDa
- TOR Serine-Threonine Kinases
- PTEN Phosphohydrolase
- PTEN protein, human
- Sirolimus
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Topics |
- Amino Acid Substitution
- Antibiotics, Antineoplastic
(agonists, pharmacology, therapeutic use)
- Breast Neoplasms
(drug therapy, enzymology, genetics)
- Cell Line, Tumor
- Doxorubicin
(agonists, pharmacology, therapeutic use)
- Drug Resistance, Neoplasm
(drug effects, genetics)
- Drug Synergism
- Female
- Gene Expression
- Humans
- Mutation, Missense
- PTEN Phosphohydrolase
(antagonists & inhibitors, genetics, metabolism)
- Protein Kinases
(genetics, metabolism)
- Proto-Oncogene Proteins c-akt
(genetics, metabolism)
- Ribosomal Protein S6 Kinases, 70-kDa
(genetics, metabolism)
- Signal Transduction
(drug effects, genetics)
- Sirolimus
(agonists, pharmacology, therapeutic use)
- TOR Serine-Threonine Kinases
- Transfection
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