Laparoscopy and intersex: report of 5 cases of male pseudohermaphroditism.

Abstract

From May, 1999 to August, 2006, we performed laparoscopic diagnosis and treatment for 103 cases of impalpable testes. Among those we found 5 cases of male pseudohermaphroditism of different etiologies. Three males presented by impalpable testes with ambiguous genitalia and 2 females presented by primary amenorrhea. All of them have 46-XY normal male chromosomal pattern. In the first 3 cases, the etiology was complete gonadal dysgenesis, and 2 cases with persistent Mullerian syndrome. Timed gonadectomy for the first case and laparoscopic orchiopexy for the other 2 cases were performed. For the other 2 female cases, the etiology was complete androgen insensitivity syndrome and laparoscopic bilateral orchiectomy was performed for both of them. All the procedures were done without complications with satisfactory results.

• Authors: Mohamed Gad El-Moula, Hirofumi Izaki, Fathy El-Anany, Alaa Abd El-Moneim, Abd El-Moneim El-Haggagy, Yasser Abdelsalam, Ahmad Abolyosr, Tomoteru Kishimoto, Natsuo Oka, Masayuki Takahashi, Tomoharu Fukumori, Hiro-Omi Kanayama
• Journal: The journal of medical investigation : JMI (J Med Invest) Vol. 55 Issue 1-2 Pg. 147-50 (Feb 2008) ISSN: 1343-1420 [Print] Japan
• PMID: 18319558 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Androgen-Insensitivity Syndrome (complications)
• Child
• Child, Preschool
• Constriction, Pathologic (complications)
• Disorders of Sex Development (diagnosis, etiology, genetics, surgery)
• Female
• Gonadal Dysgenesis (complications)
• Gonads (surgery)
• Humans
• Laparoscopy
• Male
• Mullerian Ducts (pathology)
• Treatment Outcome