Abstract |
Test parameters and clinical impact of the direct tube coagulase test (DTCT) for rapid identification of Staphylococcus aureus from blood culture were investigated. The sensitivity of the DTCT at 4 h using saline dilution was 96%, compared with 93% using serum separator tubes; specificity was 100% for both methods. Among 32 patients with S. aureus bacteraemia, treatment modifications were based on microbiology results from the primary source of infection in 12 patients, on a Gram's stain from blood culture in seven patients, and on the DTCT in nine patients. The DTCT is a valuable adjunct in the routine microbiology laboratory because of its good performance, technical simplicity and low cost.
|
Authors | P D J Sturm, D Kwa, F J Vos, C J M Bartels, T Schülin |
Journal | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
(Clin Microbiol Infect)
Vol. 14
Issue 5
Pg. 510-3
(May 2008)
ISSN: 1198-743X [Print] England |
PMID | 18318744
(Publication Type: Journal Article)
|
Chemical References |
- Anti-Infective Agents
- Coagulase
|
Topics |
- Anti-Infective Agents
(therapeutic use)
- Bacteremia
(diagnosis, drug therapy)
- Bacteriological Techniques
(methods)
- Coagulase
- Humans
- Staphylococcal Infections
(diagnosis, drug therapy)
- Staphylococcus aureus
(isolation & purification)
|