[Treatment of antiphospholipid syndrome].

Abstract

The antiphospholipid syndrome (APS) is a disorder of recurrent thrombosis and/or pregnancy loss associated with the presence of antiphospholipid antibodies and persistently positive lupus anticoagulant, anticardiolipin or anti beta2-glycoprotein1. Oral anticoagulants are the best available and most effective treatment for the secondary prevention of recurrent venous or arterial thrombosis. Patients with APS are treated with long-term therapy to prolong the INR to 2.0-3.0. Low-molecular-weight heparin in combination with low-aspirin dose is a reasonable strategy to avoid pregnancy loss in women with this syndrome.

• Authors: J A Páramo, R García, P Rodríguez, E Panizo, R Lecumberri
• Journal: Revista de medicina de la Universidad de Navarra (Rev Med Univ Navarra) 2007 Oct-Dec Vol. 51 Issue 4 Pg. 38-41 ISSN: 0556-6177 [Print] Spain
• Vernacular Title: Tratamiento del síndrome antifosfolípido.
• PMID: 18303659 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Anticoagulants
• Heparin, Low-Molecular-Weight

Topics

• Aged
• Anticoagulants (therapeutic use)
• Antiphospholipid Syndrome (drug therapy)
• Female
• Heparin, Low-Molecular-Weight (therapeutic use)
• Humans