Abstract | PURPOSE:
Adenoid cystic carcinomas are rare tumours. Regional lymphatic spread is rather uncommon. Distant metastases occur in approximately half of all patients. High local failure rates of up to 50% after surgery have been reported. Even after adjuvant radiation, the results remain poor for locally advanced tumours after incomplete resection. We report on a safe and effective salvage option in the treatment of adenoid cystic carcinoma. MATERIAL AND METHODS: A 44 year old woman with the diagnosis of adenoid cystic carcinoma of the oropharynx and simultaneous pulmonary metastases received a mixed beam photon radiotherapy and a neutron boost. Three years later, the patient developed a dysphagia grade 2, dysarthria and pain. A local recurrence in the base of tongue and floor of mouth was histologically confirmed. RESULTS: Because of the local symptoms, we offered the patient Ir-192-HDR brachytherapy with palliative intent. Under general anaesthesia, eight needles were implanted into the palpable tumour. On the basis of a pretreatment MRI, a single dose of 5 Gy encompassing the palpable tumour was given to a total dose of 15 Gy. The patient remains free from local symptoms at 8 month after brachytherapy. CONCLUSION:
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Authors | H Badakhshi, S Marnitz, H Scherer, V Budach, A Haisch |
Journal | HNO
(HNO)
Vol. 56
Issue 3
Pg. 328-31
(Mar 2008)
ISSN: 1433-0458 [Electronic] Germany |
Vernacular Title | Adenoidzystisches Karzinom des Oropharynx. Brachytherapie zur Behandlung eines lokalen Rezidivs. |
PMID | 18288466
(Publication Type: Case Reports, English Abstract, Journal Article)
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Topics |
- Adult
- Brachytherapy
(methods)
- Carcinoma, Adenoid Cystic
(diagnosis, radiotherapy)
- Female
- Humans
- Neoplasm Recurrence, Local
(radiotherapy)
- Oropharyngeal Neoplasms
(diagnosis, radiotherapy)
- Palliative Care
(methods)
- Treatment Outcome
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