Abstract | OBJECTIVE: To discuss the sentinel lymph node (SLN) mapping technique in colorectal cancer and its feasibility and utility. METHODS: The dye lymphazurin was injected subserosally around the tumor during operation in 43 colorectal cancer, 20 males and 25 females, aged 49.5 (27 - 72) so as to find the SLNs. Fast-frozen pathology and routine pathology were performed too. RESULTS: SLN was successfully identified in 42 of the 45 patients, with a successful biopsy rate of 93.3%. In these 45 patients, there were 250 lymph nodes examined, of which 52 nodes were identified as SLNs. The sensitivity was 90.4% (20/22), the specificity was 95.2% [(20 + 20)/42], and the false negative rate was 15% (3/20). CONCLUSION: SLN mapping in colorectal cancer plays an important role in diagnosing metastasis of lymph nodes, and can be used to direct the clinical surgery.
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Authors | Yang-de Zhang, Bu-Ning Tian, Hao Li, Deng-Gao Zhai |
Journal | Zhonghua yi xue za zhi
(Zhonghua Yi Xue Za Zhi)
Vol. 87
Issue 44
Pg. 3125-6
(Nov 27 2007)
ISSN: 0376-2491 [Print] China |
PMID | 18269871
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Rosaniline Dyes
- iso-sulfan blue
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Topics |
- Adult
- Aged
- Colorectal Neoplasms
(pathology)
- Female
- Humans
- Lymph Nodes
(pathology)
- Lymphatic Metastasis
(diagnosis)
- Male
- Middle Aged
- Rosaniline Dyes
(administration & dosage)
- Sensitivity and Specificity
- Sentinel Lymph Node Biopsy
(methods)
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