Adamantane-resistant influenza infection during the 2004-05 season.

Abstract

Adamantane-resistant influenza A is an emerging problem, but infections caused by resistant and susceptible viruses have not been compared. We identified adamantane resistance in 47% of 152 influenza A virus (H3N2) isolates collected during 2005. Resistant and susceptible viruses caused similar symptoms and illness duration. The prevalence of resistance was highest in children.

• Authors: Mahbubur Rahman, Rick A Bright, Burney A Kieke, James G Donahue, Robert T Greenlee, Mary Vandermause, Amanda Balish, Angela Foust, Nancy J Cox, Alexander I Klimov, David K Shay, Edward A Belongia
• Journal: Emerging infectious diseases (Emerg Infect Dis) Vol. 14 Issue 1 Pg. 173-6 (Jan 2008) ISSN: 1080-6040 [Print] United States
• PMID: 18258102 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Antiviral Agents
• Adamantane

Topics

• Adamantane (therapeutic use)
• Adolescent
• Adult
• Aged
• Antiviral Agents (therapeutic use)
• Child
• Child, Preschool
• Cohort Studies
• Disease Outbreaks
• Drug Resistance, Viral (genetics)
• Female
• Humans
• Infant
• Influenza A Virus, H3N2 Subtype (drug effects, genetics, isolation & purification)
• Influenza B virus (drug effects)
• Influenza, Human (drug therapy, epidemiology, genetics)
• Male
• Middle Aged
• Wisconsin (epidemiology)