Efficacy of etanercept and complete decongestive physical therapy in bilateral lower-limb lymphoedema associated with rheumatoid arthritis: a case report.

A 54-y-old patient with rheumatoid arthritis (RA) and bilateral lower-limb lymphoedema is presented. Complete decongestive physical therapy (CDP) is the cornerstone of the management programme in all patients suffering from lymphoedema associated with RA, but it is not clear which therapy is the most effective in decreasing the oedema. We report on a patient with bilateral lower-limb lymphoedema associated with RA who, after receiving etanercept and CDP, showed moderate improvement. There is little information on the benefit of etanercept therapy for the extra-articular manifestations of RA. Further research is necessary to confirm the beneficial effect of etanercept and CDP.
AuthorsSibel Eyigor, Hale Karapolat, Yeşim Kirazli
JournalAdvances in therapy (Adv Ther) Vol. 25 Issue 1 Pg. 23-8 (Jan 2008) ISSN: 0741-238X [Print] United States
PMID18227980 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antirheumatic Agents
  • Immunoglobulin G
  • Receptors, Tumor Necrosis Factor
  • Tumor Necrosis Factor-alpha
  • Etanercept
  • Antirheumatic Agents (therapeutic use)
  • Arthritis, Rheumatoid (complications)
  • Combined Modality Therapy
  • Etanercept
  • Female
  • Humans
  • Immunoglobulin G (therapeutic use)
  • Lower Extremity
  • Lymphedema (etiology, therapy)
  • Middle Aged
  • Physical Therapy Modalities
  • Receptors, Tumor Necrosis Factor (therapeutic use)
  • Tumor Necrosis Factor-alpha (antagonists & inhibitors)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: