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Ictal SPECT in Sturge-Weber syndrome.

Abstract
We report on a patient with right-sided Sturge-Weber syndrome (SWS), in whom earlier functional hemispherectomy failed. Subtraction of ictal and interictal single-photon-emission-computed-tomography (SPECT) superimposed on individual MRI showed a right fronto-orbital hyperperfusion, with a left-sided EEG seizure pattern. Ictal SPECT supported our assumption that right frontal originated seizure pattern propagated to left hemisphere via the remaining right frontal bridge. Right orbito-frontal resection and disconnection from corpus callosum resulted in seizure freedom.
AuthorsOzgür Bilgin, Christian Vollmar, Aurelia Peraud, Christian la Fougere, Pedro Beleza, Soheyl Noachtar
JournalEpilepsy research (Epilepsy Res) Vol. 78 Issue 2-3 Pg. 240-3 (Feb 2008) ISSN: 0920-1211 [Print] Netherlands
PMID18222066 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anticonvulsants
Topics
  • Anticonvulsants (therapeutic use)
  • Child
  • Corpus Callosum (surgery)
  • Drug Resistance
  • Electroencephalography
  • Frontal Lobe (surgery)
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Male
  • Neurosurgical Procedures
  • Paresis (etiology)
  • Seizures (diagnostic imaging, etiology)
  • Sturge-Weber Syndrome (complications, diagnostic imaging)
  • Tomography, Emission-Computed, Single-Photon

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