Abstract | BACKGROUND: OBJECTIVE: METHODS: RESULTS: There was no significant change in any measurement of oxidative damage, total antioxidant status, HbA1c, or microalbuminuria prevalence after treatment with either placebo or CRLA. CONCLUSION: In this pilot study, CRLA was not an effective treatment for decreasing oxidative damage in T1D, although efficacy may have been limited by issues with compliance.
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Authors | Eric A Huang, Stephen E Gitelman |
Journal | Pediatric diabetes
(Pediatr Diabetes)
Vol. 9
Issue 3 Pt 2
Pg. 69-73
(Jun 2008)
ISSN: 1399-5448 [Electronic] Denmark |
PMID | 18221433
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
- Delayed-Action Preparations
- Placebos
- Thiobarbituric Acid Reactive Substances
- Thioctic Acid
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Topics |
- Administration, Oral
- Adolescent
- Age of Onset
- Body Mass Index
- Body Weight
- Child
- Delayed-Action Preparations
- Diabetes Mellitus, Type 1
(drug therapy, physiopathology)
- Female
- Humans
- Male
- Oxidative Stress
(drug effects)
- Placebos
- Puberty
- Reference Values
- Thiobarbituric Acid Reactive Substances
(metabolism)
- Thioctic Acid
(administration & dosage, therapeutic use)
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