Abstract | BACKGROUND: METHODS: We analyzed 345 IDP on CNB; 142 (41.2%) received a subsequent surgical excision while 203 (58.8%) cases did not. Specimens were categorized as IDP, IPD+ADH, IDP+ALH, and DCIS. In patients with surgical follow-up the upgrade to a lesion of greater clinical significance was analyzed according to race, clinical presentation and multiplicity of papillomas. RESULTS: Of the 142 cases, 125 (93.9%) patients had a single IDP, while 17 cases were among 8 patients with multiple IDPs. Patients were predominantly asymptomatic with CNB obtained as follow-up to an abnormal mammogram. Among solitary benign IDP, nearly 25% were upgraded (p < 0.001): 14.0% to ADH and 10.5% to DCIS. For patients with IDP+ADH on initial CNB, 22.2% were upgraded to DCIS. Of the asymptomatic cases 11.4% were upgraded to DCIS, while none of the symptomatic patients showed such upgrade (p < 0.001). In patients with no surgical excision 17 (8.3%) continue to have an abnormal mammogram. CONCLUSIONS: We recommend routine mammogram and surgical excision of all IDPs identified on CNB because almost one-fourth (24.5%) of solitary IDP at CNB were upgraded to either ADH or DCIS and the majority of cases were asymptomatic.
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Authors | Monica Rizzo, Mary Jo Lund, Gabriela Oprea, Matthew Schniederjan, William C Wood, Marina Mosunjac |
Journal | Annals of surgical oncology
(Ann Surg Oncol)
Vol. 15
Issue 4
Pg. 1040-7
(Apr 2008)
ISSN: 1534-4681 [Electronic] United States |
PMID | 18204989
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Biopsy, Needle
- Breast Neoplasms
(diagnostic imaging, pathology, surgery)
- Carcinoma, Intraductal, Noninfiltrating
(pathology)
- Female
- Follow-Up Studies
- Humans
- Hyperplasia
- Middle Aged
- Papilloma, Intraductal
(diagnostic imaging, pathology, surgery)
- Precancerous Conditions
(pathology, surgery)
- Ultrasonography
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