Abstract |
We hereby report a 1-year follow-up on eight women in the first North America trial in which stress urinary incontinence (SUI) was treated with muscle-derived stem cell injections. Mean and median follow-up in this group was 16.5 and 17 months (range 3-24 months). Improvement in SUI was seen in five of eight women, with one achieving total continence. Onset of improvement was between 3 and 8 months after injection. Cure or improvement continued at a median of 10 months. No serious adverse events were reported.
|
Authors | L K Carr, D Steele, S Steele, D Wagner, R Pruchnic, R Jankowski, J Erickson, J Huard, M B Chancellor |
Journal | International urogynecology journal and pelvic floor dysfunction
(Int Urogynecol J Pelvic Floor Dysfunct)
Vol. 19
Issue 6
Pg. 881-3
(Jun 2008)
England |
PMID | 18204978
(Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
|
Topics |
- Adult
- Aged
- Feasibility Studies
- Female
- Humans
- Middle Aged
- Myoblasts
(transplantation)
- Pilot Projects
- Stem Cell Transplantation
- Transplantation, Autologous
- Urinary Incontinence, Stress
(therapy)
|