[Experimental study on combined treatment in smoke inhalation injury].

Abstract

Forty-two healthy dogs were randomly divided equally into a control group (CG) and a treated group (TG). All were inflicted with severe smoke inhalation injury and pulmonary was demonstrated. The dogs in TG were treated with injection of shenmai zhusheye, ketoprofen, anisodamine, sodium aesculin, hydrocortisone succinate, vitamin C and E, penicillin, amikacin, oxygen inhalation and airway suctioning after injury. The results showed that the increase in extravascular lung water volume, lung edema shadow in x-ray films, elevation of lung vascular resistance, carbonemia, hypoxemia, respiratory alkalosis, metabolic acidosis, dyspnea, dry and moist rales of the lungs, reduction of tidal volume, etc, were markedly improved in TG as compared with that of CG. It indicated that the pulmonary edema and lung dysfunction was markedly ameliorated in TG. The mortality was 19.1% in TG, which was significant lower than that of CG which was 47.6%.

• Authors: K Y Jiang
• Journal: Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns (Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi) Vol. 7 Issue 4 Pg. 278-81, 319 (Dec 1991) ISSN: 1000-7806 [Print] China
• PMID: 1811846 (Publication Type: English Abstract, Journal Article)

Chemical References

• Drugs, Chinese Herbal
• Solanaceous Alkaloids
• Vasodilator Agents
• anisodamine

Topics

• Animals
• Dogs
• Drugs, Chinese Herbal (therapeutic use)
• Male
• Pulmonary Edema (drug therapy, etiology)
• Smoke Inhalation Injury (complications, drug therapy)
• Solanaceous Alkaloids (therapeutic use)
• Vasodilator Agents (therapeutic use)