Severe rhabdomyolysis after excessive bodybuilding.

Abstract

A 46-year-old male subject performed excessive physical exertion during 4-6 h in a studio for body builders during 5 days. He was not practicing sport prior to this training and denied the use of any aiding substances. Despite muscle aching already after 1 day, he continued the exercises. After the last day, he recognized tiredness and cessation of urine production. Two days after discontinuation of the training, a Herpes simplex infection occurred. Because of acute renal failure, he required hemodialysis. There were absent tendon reflexes and creatine kinase (CK) values up to 208 274 U/L (normal: <170 U/L). After 2 weeks, CK had almost normalized and, after 4 weeks, hemodialysis was discontinued. Excessive muscle training may result in severe, hemodialysis-dependent rhabdomyolysis. Triggering factors may be prior low fitness level, viral infection, or subclinical metabolic myopathy.

• Authors: J Finsterer, G Zuntner, M Fuchs, A Weinberger
• Journal: The Journal of sports medicine and physical fitness (J Sports Med Phys Fitness) Vol. 47 Issue 4 Pg. 502-5 (Dec 2007) ISSN: 0022-4707 [Print] Italy
• PMID: 18091694 (Publication Type: Case Reports, Journal Article)

Chemical References

• Myoglobin

Topics

• Austria
• Crush Syndrome (physiopathology)
• Humans
• Male
• Middle Aged
• Myoglobin (metabolism)
• Renal Dialysis
• Renal Insufficiency
• Rhabdomyolysis (etiology, physiopathology)
• Severity of Illness Index
• Weight Lifting (physiology)