DEET microencapsulation: a slow-release formulation enhancing the residual efficacy of bed nets against malaria vectors.

Abstract

Textile materials treated with synthetic repellents have the potential to provide protection against insect disease vectors but lack the residual activity necessary to achieve a prolonged effect or to be cost-effective. DEET MC is a formulation of DEET (N,N diethyl-m-toluamide) in which the repellent is gradually released from a capsule that binds the repellent. An experiment carried out on DEET-treated mosquito netting showed that the formulation repels, inhibits blood-feeding and kills mosquitoes for a period of at least 6 months under laboratory conditions. Such formulations may have the potential for use on nets against pyrethroid-resistant mosquitoes or on clothing or bedding materials distributed in disasters, emergencies or refugee camp situations.

• Authors: Raphael N'guessan, Bart G J Knols, Cedric Pennetier, Mark Rowland
• Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene (Trans R Soc Trop Med Hyg) Vol. 102 Issue 3 Pg. 259-62 (Mar 2008) ISSN: 0035-9203 [Print] England
• PMID: 18082862 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Insect Repellents
• Pyrethrins
• DEET

Topics

• Animals
• Anopheles
• Bedding and Linens (statistics & numerical data)
• Culex
• DEET (administration & dosage)
• Drug Compounding
• Humans
• Insect Bites and Stings (parasitology)
• Insect Repellents (administration & dosage)
• Insecticide Resistance
• Malaria (prevention & control)
• Mosquito Control (methods)
• Pyrethrins
• Statistics as Topic
• Time Factors