Hypnic headache responsive to low-dose topiramate: a case report.

Abstract

This is a clinical report of a 63-year-old woman, with a 3-year history of severe episodes of hypnic headache responding to low-doses of topiramate (25 mg at bedtime). Topiramate has been used at the dosage of 100 mg/day for hypnic headache prevention in one recent case report with benefit. This report confirms the efficacy of topiramate in hypnic headache even using low-dose regimen therapy.

• Authors: Massimo Autunno, Corrado Messina, Anita Blandino, Carmelo Rodolico
• Journal: Headache (Headache) Vol. 48 Issue 2 Pg. 292-4 (Feb 2008) ISSN: 0017-8748 [Print] United States
• PMID: 18081825 (Publication Type: Case Reports, Journal Article)

Chemical References

• Neuroprotective Agents
• Topiramate
• Fructose

Topics

• Dose-Response Relationship, Drug
• Female
• Fructose (analogs & derivatives, therapeutic use)
• Headache Disorders, Primary (drug therapy)
• Humans
• Middle Aged
• Neuroprotective Agents (therapeutic use)
• Topiramate