Abstract |
We investigated the effects of castration on the development of lymphoid organs (bursa of Fabricius, thymus, and spleen) in the Japanese quail during 4-8 weeks of age under a long photoperiod (16L:8D) and the effect of testosterone implantation on the involution of the lymphoid organs under long (16L:8D) and short (8L:16D) photoperiods. Under 16L:8D, the bursa of Fabricius and thymus in intact quail grew rapidly and reached a peak at 6 weeks of age and regressed thereafter. In contrast, development of the lymphoid organs in castrated quail was well correlated with the body growth. Testosterone treatment induced a significant reduction in relative bursal weight to body weight at 6 weeks of age under 16L:8D and 8 weeks of age under 16L:8D and 8L:16D, in relative thymus weight at 6 weeks of age under 16L:8D and 8L:16D, and in relative spleen weight at 6 weeks of age under 8L:16D. Thus, we conclude that gonadal hormones play an important role in the development and involution of lymphoid organs.
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Authors | Y Mase, T Oishi |
Journal | General and comparative endocrinology
(Gen Comp Endocrinol)
Vol. 84
Issue 3
Pg. 426-33
(Dec 1991)
ISSN: 0016-6480 [Print] United States |
PMID | 1808023
(Publication Type: Journal Article)
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Chemical References |
- Drug Implants
- Testosterone
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Topics |
- Aging
(physiology)
- Analysis of Variance
- Animals
- Body Weight
- Bursa of Fabricius
(anatomy & histology, drug effects, growth & development)
- Castration
- Coturnix
(growth & development)
- Drug Implants
- Male
- Organ Size
- Spleen
(anatomy & histology, drug effects, growth & development)
- Testis
(drug effects, physiology)
- Testosterone
(administration & dosage, pharmacology)
- Thymus Gland
(anatomy & histology, drug effects, growth & development)
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