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Clomiphene citrate for treatment refractory chronic cluster headache.

Abstract
A treatment refractory chronic cluster headache patient is presented who became cluster-free on clomiphene citrate. The author has previously reported a SUNCT patient responding to clomiphene citrate. Hypothalamic hormonal modulation therapy with clomiphene citrate may become a new preventive choice for trigeminal autonomic cephalalgias. The possible mechanism of action of clomiphene citrate for cluster headache prevention will be discussed.
AuthorsTodd Rozen
JournalHeadache (Headache) Vol. 48 Issue 2 Pg. 286-90 (Feb 2008) ISSN: 0017-8748 [Print] United States
PMID18070056 (Publication Type: Journal Article, Review)
Chemical References
  • Estrogen Antagonists
  • Clomiphene
Topics
  • Adult
  • Clomiphene (therapeutic use)
  • Cluster Headache (drug therapy)
  • Estrogen Antagonists (therapeutic use)
  • Humans
  • Male

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