HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Immunohistochemical study on clear cell chondrosarcoma].

Abstract
Clear cell chondrosarcoma, a subtype and separate entity from the conventional chondrosarcoma, is characterized by its special histologic features, site of predilection, slow growth and better prognosis. Three cases are presented with elucidation of clinicopathologic correlation and detection by ABC immunohistochemical method using several antibodies. The observation of positive reaction to S-100 protein, vimentin, anti-alpha-chymotrypsin and Lysozyme by the tumor cells of clear cell chondrosarcoma, similar to chondrosarcoma and chondroblastoma, proves that this tumor has its origin from the cartilaginous tissue. It was found for the first time that the clear cell chondrosarcoma was positive for wheat germ agglutinin and concanavalin A. The authors believe that clear cell chondrosarcoma may result from the anaplastic change of chondroblastoma cells into another subtype of that tumor. The osteoblastlike multinucleated giant cells, retaining the antigens of phagocytes, are not considered to be neoplastic.
AuthorsL T Wang
JournalZhonghua zhong liu za zhi [Chinese journal of oncology] (Zhonghua Zhong Liu Za Zhi) Vol. 13 Issue 4 Pg. 306-8 (Jul 1991) ISSN: 0253-3766 [Print] China
PMID1806353 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Wheat Germ Agglutinins
  • Concanavalin A
Topics
  • Adult
  • Bone Neoplasms (diagnosis, metabolism)
  • Chondrosarcoma (diagnosis, metabolism)
  • Concanavalin A (analysis)
  • Female
  • Femoral Neoplasms (diagnosis, metabolism)
  • Histocytochemistry
  • Humans
  • Immunohistochemistry
  • Male
  • Tibia
  • Wheat Germ Agglutinins (analysis)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: