Abstract | BACKGROUND: OBJECTIVES: The purpose of the present study was, therefore, to assess the frequency and duration of episodes of MB prior to and during treatment with nCPAP. METHODS: MB was recorded prior to and during nCPAP with a closely fitting mouth mask connected to a pneumotachograph and nasal flow was measured via nasal prongs. MB episodes were expressed as the number of events divided by total sleep time x 60, to give the MB event index per hour of sleep. MB time divided by total sleep time x 60 was calculated in minutes to get the MB time index per hour of sleep. PATIENTS: Eleven male patients with OSAS (mean age 57.9 +/- 8.3 years, body mass index 30.2 +/- 3.8) were recruited to the study. RESULTS: Prior to nCPAP, the apnea/hypopnea index was 55.8 +/- 26 and decreased during nCPAP to 8.0 +/- 3.4. The lowest SaO2 measured was 82.9 +/- 4.7%, and increased to 87.5 +/- 2.7% under nCPAP. The mean nCPAP was 7.8 +/- 1.6 cm H2O. MB event index per hour of sleep decreased from 35.2 +/- 19.7 prior to treatment to 5.0 +/- 5.2 under nCPAP (p < 0.01). In 52.2 +/- 27.4% of obstructive respiratory events, MB started at the end of an apnea/hypopnea episode, decreasing to 8.5 +/- 12.5% with nCPAP treatment. MB time index per hour of sleep was reduced from 13.5 +/- 10.2 min prior to treatment to 4.6 +/- 5.5 min under nCPAP (p < 0.05). CONCLUSIONS: In OSAS patients, MB episodes often appear at the termination of an apnea/hypopnea episode. In many cases, MB episodes can be markedly reduced by nCPAP treatment. When patients on nCPAP complain of dry mouth, appropriate measurements should be performed to verify MB.
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Authors | Karl Heinz Ruhle, Georg Nilius |
Journal | Respiration; international review of thoracic diseases
(Respiration)
Vol. 76
Issue 1
Pg. 40-5
( 2008)
ISSN: 1423-0356 [Electronic] Switzerland |
PMID | 18042974
(Publication Type: Journal Article)
|
Copyright | 2007 S. Karger AG, Basel. |
Topics |
- Continuous Positive Airway Pressure
- Humans
- Male
- Middle Aged
- Mouth Breathing
- Polysomnography
- Sleep Apnea, Obstructive
(physiopathology, therapy)
- Sleep Stages
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