Abstract | OBJECTIVE: To investigate the protective effect and mechanism of Yimucao (Herba leonuri) injection against experimental cerebral ischemia. METHODS: RESULTS: Yimucao injection significantly lowered the cerebral index of mice with cerebral ischemia, prolonged the survival time of mice poisoned with potassium cyanide, resulting also in significantly decreased MDA content and increased activities of SOD and LDH in the brain tissue of rats after a 10-min cerebral ischemia followed by 30 min of reperfusion. CONCLUSION:
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Authors | Chong-Xuan Xie, Yu-Qun Yang, Jian-Pei Lu, Mian Tang, We Zhou |
Journal | Nan fang yi ke da xue xue bao = Journal of Southern Medical University
(Nan Fang Yi Ke Da Xue Xue Bao)
Vol. 27
Issue 10
Pg. 1528-30
(Oct 2007)
ISSN: 1673-4254 [Print] China |
PMID | 17959532
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Drugs, Chinese Herbal
- Protective Agents
- Malondialdehyde
- L-Lactate Dehydrogenase
- Superoxide Dismutase
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Topics |
- Animals
- Brain Ischemia
(drug therapy, enzymology, metabolism)
- Disease Models, Animal
- Drugs, Chinese Herbal
(administration & dosage)
- Female
- Humans
- L-Lactate Dehydrogenase
(metabolism)
- Male
- Malondialdehyde
(metabolism)
- Mice
- Protective Agents
(administration & dosage)
- Rats
- Rats, Sprague-Dawley
- Superoxide Dismutase
(metabolism)
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