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[Which therapy for acute and chronic migrains?].

Abstract
The onset of a migraine attack is associated with the activation of the trigemino-vascular system. Early intervention with triptans, which inhibit this activation is an effective treatment for migraine attacks. To avoid a cutaneous allodynia it is necessary to introduce as soon as possible the treatment with triptans. Drugs useful in the migraine prophylaxis tend to reduce the neuronal excitability in different areas of the central nervous system. The new definition of a chronic migraine is presented. This chronic migraine is frequently the result of an overuse of triptans. The practical aspects of the therapy of this specific migraine are described.
AuthorsFranco Regli, Annelise Dewarrat
JournalRevue medicale suisse (Rev Med Suisse) Vol. 3 Issue 125 Pg. 2130-4 (Sep 19 2007) ISSN: 1660-9379 [Print] Switzerland
Vernacular TitleMigraine épisodique et migraine chronique: quel traitement?
PMID17939532 (Publication Type: Journal Article, Review)
Chemical References
  • Adrenergic beta-Antagonists
  • Anticonvulsants
  • Tryptamines
  • Topiramate
  • Fructose
Topics
  • Acute Disease
  • Adrenergic beta-Antagonists (therapeutic use)
  • Anticonvulsants (therapeutic use)
  • Chronic Disease
  • Fructose (analogs & derivatives, therapeutic use)
  • Humans
  • Hyperalgesia (etiology, prevention & control)
  • Migraine Disorders (complications, drug therapy)
  • Topiramate
  • Tryptamines (therapeutic use)

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