Treatment of immobilization hypercalciuria using weekly alendronate in two quadriplegic patients.

Abstract

Metabolic and urinary problems encountered in spinal cord injury patients are multifaced. We report two patients with high-level spinal cord injuries who have developed hypercalciuria after admission to the rehabilitation unit. To establish a clean intermittent self-catheterization programme, the hypercalciuria was treated successfully with alendronate. Twenty-four-hour urinary calcium excretion decreased significantly after medical treatment for hypercalciuria. Since high-level quadriplegic patients may not be mobilized in the acute phase of the rehabilitation, use of alendronate for preventing hypercalciuria and maintaining a successful clean intermittent self-catheterization programme can be considered as a supportive/complementary measure.

• Authors: Ayce Atalay, Nur Turhan
• Journal: International urology and nephrology (Int Urol Nephrol) Vol. 40 Issue 2 Pg. 259-61 ( 2008) ISSN: 0301-1623 [Print] Netherlands
• PMID: 17934791 (Publication Type: Case Reports, Journal Article)

Chemical References

• Bone Density Conservation Agents
• Alendronate

Topics

• Adult
• Alendronate (administration & dosage)
• Bone Density Conservation Agents (administration & dosage)
• Humans
• Hypercalciuria (drug therapy, etiology)
• Immobilization (adverse effects)
• Male
• Quadriplegia (complications)
• Spinal Cord Injuries (complications, therapy)