Abstract |
109 patients with vestibular disease were included in two different treatments with amitriptyline (Group A:53 patients with depressive symptoms), or flunarizine (Group B: 56 patients). Vertiginous symptoms, basic vestibular exploration, depressive disorder, cochlear symptoms, vegetative disorders and headache were evaluated. Among the patients treated with amitriptyline a significant decrease in the vertiginous symptoms were observed. The possible mechanism of action were analyzed too.
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Authors | J L Pardal Refoyo, L D Beltrán Mateos |
Journal | Acta otorrinolaringologica espanola
(Acta Otorrinolaringol Esp)
1991 Nov-Dec
Vol. 42
Issue 6
Pg. 433-7
ISSN: 0001-6519 [Print] Spain |
Vernacular Title | Ensayo de amitriptilina versus flunarizina como tratamiento en patología vestibular. Estudio preliminar. |
PMID | 1790064
(Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)
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Chemical References |
- Amitriptyline
- Flunarizine
|
Topics |
- Amitriptyline
(administration & dosage, adverse effects, therapeutic use)
- Depression
(drug therapy)
- Female
- Flunarizine
(administration & dosage, adverse effects, therapeutic use)
- Humans
- Male
- Middle Aged
- Time Factors
- Vertigo
(drug therapy)
- Vestibular Diseases
(drug therapy)
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