Single preoperative bladder instillation of povidone-iodine for the prevention of postprostatectomy bacteriuria and wound infection.

Abstract

OBJECTIVE:

To study the effectiveness of preoperative bladder washing with povidone-iodine to prevent postprostatectomy wound infection.

DESIGN:

Patients with an indwelling catheter and scheduled for prostatectomy were divided into two groups. In patients in group 1 (n = 76) the indwelling catheter was simply removed without bladder irrigation. Patients in group 2 (n = 80) had their bladder washed with a nondiluted solution of povidone-iodine before surgery.

PATIENTS:

One hundred fifty-six consecutive patients with an indwelling catheter and bacteriuria. Mean age was 64 years. All patients had an open prostatectomy during the 12-month study period. Patients undergoing open prostatectomy during the first 6 months of the study had no bladder irrigation and served as the control group. Patients undergoing open prostatectomy during the following 6 months had a bladder instillation with povidone-iodine.

RESULTS:

Wound infection appeared in 17 of 76 patients (22.4%) without bladder washing and in 4 of 80 patients (5%) when 50 to 60 ml of the solution was retained in the bladder for 10 to 13 minutes (p = .001). The incidence of postoperative bacteriuria remained unchanged in the control group (100%) but was reduced to 22.5% in the treated group (p = .001). Statistical comparisons of incidence were done using the chi square test.

CONCLUSIONS:

It has been demonstrated that the use of preoperative bladder instillation of povidone-iodine may be highly effective in the prevention of postprostatectomy wound infection and in reducing the incidence of bacteriuria in patients with an indwelling catheter and urine colonization.

• Authors: S Richter, O Kotliroff, I Nissenkorn
• Journal: Infection control and hospital epidemiology (Infect Control Hosp Epidemiol) Vol. 12 Issue 10 Pg. 579-82 (Oct 1991) ISSN: 0899-823X [Print] United States
• PMID: 1787307 (Publication Type: Clinical Trial, Comparative Study, Journal Article)

Chemical References

• Povidone-Iodine

Topics

• Administration, Intravesical
• Aged
• Aged, 80 and over
• Bacteriuria (microbiology, prevention & control)
• Humans
• Male
• Middle Aged
• Povidone-Iodine (administration & dosage)
• Preoperative Care (methods)
• Prostatectomy
• Surgical Wound Infection (microbiology, prevention & control)
• Therapeutic Irrigation
• Urinary Bladder Diseases (microbiology, prevention & control)