Abstract | BACKGROUND: CASE REPORT: We report of a patient with leptomeningeal carcinomatosis of RCC, who 10 days after initiation of sorafenib therapy showed a noticeable decrease in contrast enhancement of the tumor in a magnetic resonance imaging (MRI) scan of the brain. This partial response was verified by an MRI scan on day 74. DISCUSSION: Results of a sub-evalution of a randomized phase III trial show that sorafenib offers encouraging activity in the treatment of patients with RCC and brain metastases. CONCLUSION:
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Authors | Oliver Ranze, Erich Hofmann, Andrea Distelrath, Heinz-Gert Hoeffkes |
Journal | Onkologie
(Onkologie)
Vol. 30
Issue 8-9
Pg. 450-1
(Sep 2007)
ISSN: 1423-0240 [Electronic] Switzerland |
PMID | 17848817
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antineoplastic Agents
- Benzenesulfonates
- Phenylurea Compounds
- Pyridines
- Niacinamide
- Sorafenib
|
Topics |
- Antineoplastic Agents
(administration & dosage)
- Benzenesulfonates
(administration & dosage)
- Carcinoma, Renal Cell
(drug therapy, secondary)
- Humans
- Kidney Neoplasms
(drug therapy)
- Male
- Meningeal Neoplasms
(drug therapy, secondary)
- Middle Aged
- Niacinamide
(analogs & derivatives)
- Phenylurea Compounds
- Pyridines
(administration & dosage)
- Sorafenib
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