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[Sensitivity of Pseudomonas mallei to fluoroquinolones and their efficacy in experimental glanders].

Abstract
Thirteen strains of P. mallei were found to be highly sensitive to ciprofloxacin and ofloxacin and resistant to norfloxacin. Ciprofloxacin and ofloxacin showed a high efficacy on models of malleus in guinea pigs and hamsters. The animals were infected with various strains of P. mallei. In the in vitro experiments, ciprofloxacin proved to be the most active and efficient. Norfloxacin appeared to be inefficient.
AuthorsV P Batmanov
JournalAntibiotiki i khimioterapii︠a︡ = Antibiotics and chemoterapy [sic] / Ministerstvo meditsinskoĭ i mikrobiologicheskoĭ promyshlennosti SSSR (Antibiot Khimioter) Vol. 36 Issue 9 Pg. 31-4 (Sep 1991) ISSN: 0235-2990 [Print] USSR
Vernacular TitleChuvstvitel'nost' Pseudomonas mallei k ftorkhinolonam i éffektivnost' ikh pri éksperimental'nom sape.
PMID1781709 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Ciprofloxacin
  • Ofloxacin
  • Norfloxacin
Topics
  • Animals
  • Ciprofloxacin (therapeutic use)
  • Cricetinae
  • Drug Resistance, Microbial (physiology)
  • Glanders (drug therapy)
  • Guinea Pigs
  • Microbial Sensitivity Tests
  • Norfloxacin (therapeutic use)
  • Ofloxacin (therapeutic use)
  • Pseudomonas (drug effects)

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