Abstract | BACKGROUND: METHODS: This study comprised 64 cases of infiltrating ductal carcinoma in postmenopausal women divided into two groups: Group A: ER-positive, n = 35; and Group B: ER-negative, n = 29. The anti-CD34 monoclonal antibody was used as a marker for endothelial cells. Microvessel count was carried out in 10 fields per slide using a 40x objective lens (magnification 400x). Statistical analysis of the data was performed using Student's t-test (p < 0.05). RESULTS: The mean number of vessels stained with the anti-CD34 antibody in the estrogen receptor-positive and negative tumors was 23.51 +/- 1.15 and 40.24 +/- 0.42, respectively. The number of microvessels was significantly greater in the estrogen receptor-negative tumors (p < 0.001). CONCLUSION:
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Authors | Jb Parentes-Vieira, Pv Lopes-Costa, Cg Pires, Ar Dos Santos, Jd Pereira-Filho, Bb da Silva |
Journal | International seminars in surgical oncology : ISSO
(Int Semin Surg Oncol)
Vol. 4
Pg. 22
(Aug 24 2007)
ISSN: 1477-7800 [Electronic] England |
PMID | 17718911
(Publication Type: Journal Article)
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