Abstract |
The objective of this study was to investigate the efficacy, safety and tolerability of triptans in patients who suffer from familial or sporadic hemiplegic migraine. Seventy-six subjects had used triptans at least once as an abortive treatment. Average triptan response was 6.9 (SD +/-3.1) and adverse event severity 4.9 (SD +/-3.3) on a scale from 0 to 10 (no response or side effect 0, excellent response or unbearable side effects 10). None of the patients had an ischaemic stroke or a heart attack. One patient reported prolonged neurological symptoms, related to a single dose of rizatriptan, but there were no pathological findings in several MRI-scans. Triptans seem to be safe and effective treatment for most hemiplegic migraine patients.
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Authors | V Artto, M Nissilä, M Wessman, A Palotie, M Färkkilä, M Kallela |
Journal | European journal of neurology
(Eur J Neurol)
Vol. 14
Issue 9
Pg. 1053-6
(Sep 2007)
ISSN: 1468-1331 [Electronic] England |
PMID | 17718700
(Publication Type: Evaluation Study, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
- Serotonin Receptor Agonists
- Tryptamines
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Topics |
- Adult
- Female
- Humans
- Male
- Middle Aged
- Migraine with Aura
(drug therapy)
- Neurologic Examination
- Serotonin Receptor Agonists
(therapeutic use)
- Tryptamines
(therapeutic use)
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