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[Treatment of plaque-type psoriasis with cream-PUVA therapy].

Abstract
PUVA-bath therapy has developed into first line topical PUVA therapy in the treatment of psoriasis. Because of logistical and economic problems, bath PUVA may be difficult to administer. Recently, cream-PUVA therapy has been described as an alternative mode of topical therapy. We treated two patients with moderate plaque-type psoriasis with this new topical approach. 0,0006% 8-methoxypsoralen cream was applied for 1 hour, directly followed by increasing doses of UVA. The number of treatments needed for clearance were 34 and 40. The cumulative UVA dosages were 71.6 and 84 J/cm(2) respectively. Our data document that cream-PUVA therapy is an effective and safe variation of topical PUVA therapy, which may develop into first line photochemotherapy for patients with moderate plaque-type psoriasis.
AuthorsK Steinmeyer, M Grundmann-Kollmann, M Podda, R Kaufmann
JournalDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 52 Issue 10 Pg. 885-7 (Oct 2001) ISSN: 1432-1173 [Electronic] Germany
Vernacular TitleCreme-PUVA-Photochemotherapie bei chronisch stationärer Psoriasis vulgaris.
PMID17690819 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Dermatologic Agents
  • Photosensitizing Agents
  • Methoxsalen
Topics
  • Administration, Topical
  • Adult
  • Dermatologic Agents (administration & dosage)
  • Humans
  • Male
  • Methoxsalen (administration & dosage)
  • Middle Aged
  • PUVA Therapy (methods)
  • Photosensitizing Agents (administration & dosage)
  • Psoriasis (drug therapy, pathology)
  • Treatment Outcome

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