[Ultraviolet-A1 (UVA1) phototherapy in lichen sclerosus et atrophicus].

Abstract

Two patients, a nine year old girl and a 59 year old woman, presented with extensive and recalcitrant lichen sclerosus et atrophicus (LSA). Both patients were treated with low-dose ultraviolet-A1 (UVA1) phototherapy (340-400 nm) for ten weeks. The cumulative UVA1 dose was 800 J/cm(2), the single UVA1 dose was 20 J/cm(2). After 40 treatment sessions, the previously sclerotic skin lesions had almost completely cleared in both patients. In addition 20-MHz ultrasound examination and histological specimen revealed no further signs of sclerosis. UVA1 phototherapy seems to be a new and effective treatment for LSA with optimal patients' acceptance due to the absence of systemic side effects. UVA1 should be therefore considered as therapeutic option for LSA.

• Authors: A Kreuter, G von Kobyletzki, M Happe, M Herde, F Breuckmann, M Stücker, P Altmeyer
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 52 Issue 10 Pg. 878-81 (Oct 2001) ISSN: 1432-1173 [Electronic] Germany
• Vernacular Title: UVA1-Phototherapie bei Lichen sclerosus et atrophicus.
• PMID: 17690817 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Child
• Female
• Humans
• Lichen Sclerosus et Atrophicus (pathology, radiotherapy)
• Middle Aged
• Radiation Dosage
• Treatment Outcome
• Ultraviolet Therapy (methods)