Abstract | OBJECTIVES: METHODS: RESULTS: CONCLUSION: It is concluded that 3,4-DAA has both anti-inflammatory and analgesic properties, and may therefore be useful in filling an unmet need, in the treatment of rheumatoid and other forms of arthritis, especially in the light of its analgesic properties.
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Authors | J J Inglis, G Criado, M Andrews, M Feldmann, R O Williams, M L Selley |
Journal | Rheumatology (Oxford, England)
(Rheumatology (Oxford))
Vol. 46
Issue 9
Pg. 1428-32
(Sep 2007)
ISSN: 1462-0324 [Print] England |
PMID | 17644821
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents, Non-Steroidal
- ortho-Aminobenzoates
- 3-Hydroxyanthranilic Acid
- tranilast
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Topics |
- 3-Hydroxyanthranilic Acid
(pharmacology)
- Analgesics, Non-Narcotic
(therapeutic use)
- Animals
- Anti-Inflammatory Agents, Non-Steroidal
(therapeutic use)
- Arthritis, Experimental
(drug therapy, immunology, prevention & control)
- Arthritis, Rheumatoid
(drug therapy, immunology, prevention & control)
- B-Lymphocytes
(drug effects, immunology)
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical
- Hyperalgesia
(prevention & control)
- Lymphocyte Activation
(drug effects)
- Male
- Mice
- Mice, Inbred DBA
- T-Lymphocytes
(drug effects, immunology)
- ortho-Aminobenzoates
(therapeutic use)
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