Hyperbaric oxygen therapy for interstitial cystitis resistant to conventional treatments.

Abstract

We treated two cases of interstitial cystitis (IC) that were resistant to some conventional therapies with hyperbaric oxygen (HBO). Both patients underwent 20 sessions of 100% oxygen inhalation (2.0 atmosphere absolute for 60 min/day x 5 days/week for 4 weeks) in a hyperbaric chamber. The period of follow up was 12 months for case 1 and 9 months for case 2. After a course of HBO, the bladder mucosal ulcer (Hunner's ulcer) disappeared, and changes from baseline in pain and urinary frequency was constitutively inhibited. There were no adverse events during the 20 treatment sessions. One woman (case 1) had mild Eustachian tube dysfunction, resulting in a transient hearing impairment. HBO seems to be an option for treatment of IC resistant to conventional therapies.

• Authors: Tomoaki Tanaka, Hidenori Kawashima, Tetsuya Makino, Sadanori Kamikawa, Noboru Kato, Tatsuya Nakatani
• Journal: International journal of urology : official journal of the Japanese Urological Association (Int J Urol) Vol. 14 Issue 6 Pg. 563-5 (Jun 2007) ISSN: 0919-8172 [Print] Australia
• PMID: 17593107 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Cystitis, Interstitial (pathology, therapy)
• Cystoscopy
• Female
• Humans
• Hyperbaric Oxygenation (adverse effects, methods)
• Middle Aged
• Pain (pathology)
• Pain Management
• Pain Measurement
• Ulcer (pathology, therapy)
• Urination