Radiotherapy for Erdheim-Chester disease.

Abstract

A 42-year-old woman suffered from pain in both legs, and fever. She was diagnosed with Erdheim-Chester disease (ECD), based upon bone biopsy. Initially, she received steroid therapy, which led to temporary improvement. However, bone pain in the right femur was so progressive that, as a trial course of radiation therapy, she was given a total dose of 18 Gy in ten fractions to the right distal femur. She showed a gradual response, and the local pain became controllable. Erdheim-Chester disease (ECD) is an uncommon, non-Langerhans form of histiocytosis, which is characterized by radiological and pathological findings, but its treatment is still controversial. We here present a representative case report of radiotherapy for ECD.

• Authors: Katsunori Matsui, Yasushi Nagata, Masahiro Hiraoka
• Journal: International journal of clinical oncology (Int J Clin Oncol) Vol. 12 Issue 3 Pg. 238-41 (Jun 2007) ISSN: 1341-9625 [Print] Japan
• PMID: 17566851 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Adult
• Dose Fractionation, Radiation
• Erdheim-Chester Disease (complications, pathology, radiotherapy)
• Female
• Humans
• Pain, Intractable (etiology, radiotherapy)