Nosocomial meningitis in neonates caused by Streptococcus agalactiae.

Abstract

Streptococcus agalactiae is a rare cause of neonatal meningitis in the era of peripartum prophylaxis with prophylaxis with ampicillin in colonized/infected mothers. However 5 cases of meningitis among 171 cases of pediatric nosocomial meningitis database within last 15 years occurred. All 5 children were neonates (one VLBW and early gestation newborn), 2 after neurosurgery. All 5 cases were successfully cured with a combination of cefotaxim (or ceftazidim) plus aminoglycosides, in one case also with addition of vancomycin or ampicillin. However 3 of 5 cured patients had neurologic sequellae, two of them reversible hydrocephalus and in speech retardation.

• Authors: B Rudinsky, A Ondrusova, F Bauer, J Benca, M Huttova
• Journal: Neuro endocrinology letters (Neuro Endocrinol Lett) Vol. 28 Suppl 2 Pg. 30-1 (Jun 2007) ISSN: 0172-780X [Print] Sweden
• PMID: 17558374 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents

Topics

• Anti-Bacterial Agents (therapeutic use)
• Cross Infection (drug therapy, etiology, microbiology)
• Humans
• Hydrocephalus (etiology)
• Infant, Newborn
• Language Development Disorders (etiology)
• Meningitis, Bacterial (drug therapy, etiology, microbiology)
• Rare Diseases
• Retrospective Studies
• Streptococcal Infections (complications, drug therapy)
• Streptococcus agalactiae (pathogenicity)