Abstract | BACKGROUND: METHODS: The medical records and postoperative courses for patients involved in 2111 neurosurgical procedures at our institution during 1991-2005 were reviewed retrospectively to determine the incidence of PCNSI, the identity of offending organisms, and the factors associated with infection. RESULTS: The median age of patients at the time of surgery was 45 years. Of the 1587 cranial operations, 14 (0.8%) were complicated by PCNSI, whereas none of the 32 peripheral nerve operations resulted in PCNSI. The remaining 492 operative cases involved spinal surgery, of which 2 (0.4%) were complicated by PCNSI. The overall incidence of PCNSI was 0.8% (occurring after 16 of 2111 operations); the incidence of bacterial meningitis was 0.3% (occurring after 4 of 1587 operations), and the incidence of brain abscess was 0.2% (occurring after 3 of 1587 operations). The most common offending organism was Staphylococcus aureus (8 cases; 50% of infections), followed by Propionibacterium acnes (4 cases; 25% of infections). Cerebrospinal fluid leakage, diabetes mellitus, and male sex were not associated with PCNSI (P>.05). CONCLUSIONS:
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Authors | Shearwood McClelland 3rd, Walter A Hall |
Journal | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
(Clin Infect Dis)
Vol. 45
Issue 1
Pg. 55-9
(Jul 01 2007)
ISSN: 1537-6591 [Electronic] United States |
PMID | 17554701
(Publication Type: Journal Article)
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Topics |
- Central Nervous System Infections
(microbiology)
- Female
- Humans
- Incidence
- Male
- Middle Aged
- Neurosurgical Procedures
(adverse effects)
- Postoperative Period
- Spinal Nerves
(surgery)
- Surgical Wound Infection
(epidemiology, microbiology)
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