Abstract | OBJECTIVE: METHODS: We describe our experience of brown tumor lesions at different skeletal sites that were treated at our trauma centre within the last two years. This included surgical therapy for the indications (i) pain at the pelvis, (ii) increased risk for pathological fracture at the tibia and (iii) acute radicular symptoms at the lumbar spine. The literature was reviewed for the current understanding of the pathophysiology as well as therapy of brown tumor lesions in primary hyperparathyroidism. RESULTS: CONCLUSION: Patients with refractory primary hyperparathyroidism should be monitored closely by endocrinologists and the patient's serum calcium level should be adjusted as far as possible. Radiography is required only if focal bone pain or pathological fractures or radicular symptoms occur. Surgery should be considered if large bone defects with spontaneous fracture risk or increasing pain are present. Tumor curettage, Palacos plombage and less invasive stabilisation systems have proved to be acceptable surgical options.
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Authors | P N Khalil, S M Heining, R Huss, S Ihrler, M Siebeck, K Hallfeldt, E Euler, W Mutschler |
Journal | European journal of medical research
(Eur J Med Res)
Vol. 12
Issue 5
Pg. 222-30
(May 29 2007)
ISSN: 0949-2321 [Print] England |
PMID | 17513195
(Publication Type: Case Reports, Journal Article)
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Topics |
- Aged
- Humans
- Hyperparathyroidism, Primary
(complications, physiopathology)
- Male
- Orthopedic Procedures
(methods)
- Osteitis Fibrosa Cystica
(etiology, physiopathology, surgery)
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