[Round window catheter placement with dexamethasone perfusion for intractable sudden sensorineural hearing loss].

Abstract

OBJECTIVE:

To investigate the efficacy of round window catheter placement with dexamethasone perfusion for 13 patients with intractable sudden sensorineural hearing loss (SSNHL).

METHOD:

Dexamethasone (2.5 mg) was perfused transtympanically through round window catheter by Micro-infusion pump. The perfusion was taken twice a day and continued for an hour each time, for a total of 7 days.

RESULT:

Thirteen patients have been followed up for 1 month. Five of them (38.5%) were demonstrated a 17-54 dB improvement in pure-tone threshold average (PTA). The other 8 patients (61.5%) had no effect.

CONCLUSION:

Round window catheter placement with dexamethasone perfusion is a cost-effective and useful treatment for SSNHL patients who had no effect through conventional therapy, although hearing thresholds of these patients had hardly improved to normal levels.

• Authors: Xialing Sun, Jihao Ren, Yongde Lu, Tuanfang Yin, Weijing Wu, Yueying Tang, Binya Hu
• Journal: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery (Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi) Vol. 21 Issue 4 Pg. 146-8 (Feb 2007) ISSN: 2096-7993 [Print] China
• PMID: 17511168 (Publication Type: Evaluation Study, Journal Article)

Chemical References

• Dexamethasone

Topics

• Adult
• Aged
• Catheterization
• Dexamethasone (administration & dosage, therapeutic use)
• Female
• Hearing Loss, Sensorineural (drug therapy)
• Hearing Loss, Sudden (drug therapy)
• Humans
• Male
• Middle Aged
• Round Window, Ear