Exuberant molluscum contagiosum as a manifestation of the immune reconstitution inflammatory syndrome.

Abstract

Immune reconstitution inflammatory syndrome (IRIS) is a recently described entity in which severely immunodepressed HIV patients, after being started on HAART, develop inflammatory reactions to several pathogens. We present a patient who developed extensive Molluscum Contagiosum (MC) lesions shortly after being started on HAART. With the progression of immunoreconstitution, the lesions healed spontaneously. Molluscum contagiosum lesions are presumably common in IRIS but underreported. We point out this case for its striking clinical picture and well-documented relation to immunoreconstitution to draw attention to this IRIS manifestation.

• Authors: Bárbara Pereira, Cândida Fernandes, Ermelinda Nachiambo, Ma Carmo Catarino, Ana Rodrigues, Jorge Cardoso
• Journal: Dermatology online journal (Dermatol Online J) Vol. 13 Issue 2 Pg. 6 (May 01 2007) ISSN: 1087-2108 [Electronic] United States
• PMID: 17498425 (Publication Type: Case Reports, Journal Article)

Chemical References

• HLA-D Antigens

Topics

• Aged
• Antiretroviral Therapy, Highly Active (adverse effects, methods)
• Follow-Up Studies
• HIV Infections (diagnosis, drug therapy, immunology)
• HLA-D Antigens (immunology)
• Humans
• Immune Tolerance
• Immunocompromised Host
• Inflammation (immunology, physiopathology, therapy)
• Male
• Molluscum Contagiosum (chemically induced, immunology, therapy)
• Risk Assessment
• Severity of Illness Index
• Syndrome
• Viral Load