Abstract | BACKGROUND: METHODS: Fourteen episodes of NMS were prospectively identified. Patients were examined for catatonia during the course of NMS. Close monitoring of catatonia episodes and suspected cases of evolving NMS for possible NMS development provided data on the pre-NMS clinical course. All NMS episodes received benzodiazepines. Episodes with catatonia diagnosed were compared with those without catatonia, noting their presentation, clinical course and responses to treatment. RESULTS: CONCLUSIONS: The preliminary findings support the hypothesis that NMS is a heterogeneous condition including catatonic variants and non-catatonic hyperthermic extrapyramidal reactions to antipsychotics, differing in presentation, clinical course, and treatment responses.
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Authors | Joseph W Y Lee |
Journal | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists
(Ann Clin Psychiatry)
2007 Jan-Mar
Vol. 19
Issue 1
Pg. 9-16
ISSN: 1040-1237 [Print] United States |
PMID | 17453656
(Publication Type: Journal Article)
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Chemical References |
- Antipsychotic Agents
- Benzodiazepines
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Topics |
- Adolescent
- Adult
- Amnesia
(diagnosis, drug therapy)
- Antipsychotic Agents
(adverse effects, therapeutic use)
- Basal Ganglia Diseases
(chemically induced, diagnosis, drug therapy)
- Benzodiazepines
(therapeutic use)
- Bipolar Disorder
(diagnosis, drug therapy)
- Catatonia
(chemically induced, diagnosis, drug therapy)
- Delirium
(chemically induced, diagnosis, drug therapy)
- Diagnosis, Differential
- Disease Progression
- Female
- Humans
- Male
- Malignant Hyperthermia
(diagnosis, drug therapy)
- Neuroleptic Malignant Syndrome
(diagnosis, drug therapy)
- Neurologic Examination
(drug effects)
- Parkinsonian Disorders
(chemically induced, diagnosis, drug therapy)
- Psychotic Disorders
(diagnosis, drug therapy)
- Schizophrenia
(diagnosis, drug therapy)
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